Cell-cell death communication by signals passing through non-aqueous environments: A reply

The effects of the emission low intensity light from cells and organelles, known as biophotons, or ultraweak photon emission, are not well understood subject to debate. Potapovich & Kostyuk recently proposed that induction oxidative stress generates non-chemical death signals which can induce cell in neighbouring, chemically isolated (termed detector cells). Given significance these results, here we attempt replicate their findings. We found treatment “inductor cells” with duroquinone dissolved ethanol does indeed significant neighbouring “detector” relative distant control (64.53% ± 14.42 vs 99.72% 6.09 viability), closely reproducing original results. However, this was no longer true if drug a less volatile solvent, suggesting findings may have been result solvent-based transmission opposed light-based signalling.